{"id":9527,"date":"2026-07-14T19:24:04","date_gmt":"2026-07-14T19:24:04","guid":{"rendered":"https:\/\/godshand.link\/ground_post\/guideline-on-doxycycline-post-exposure-prophylaxis-for-sexually-transmitted-infections-among-men-who-have-sex-with-men-and-transgender-women\/"},"modified":"2026-07-14T19:24:04","modified_gmt":"2026-07-14T19:24:04","slug":"guideline-on-doxycycline-post-exposure-prophylaxis-for-sexually-transmitted-infections-among-men-who-have-sex-with-men-and-transgender-women","status":"publish","type":"ground_post","link":"https:\/\/godshand.link\/en_gb\/ground_post\/guideline-on-doxycycline-post-exposure-prophylaxis-for-sexually-transmitted-infections-among-men-who-have-sex-with-men-and-transgender-women\/","title":{"rendered":"Guideline on doxycycline post-exposure prophylaxis for sexually transmitted infections among men who have sex with men and transgender women"},"content":{"rendered":"<p><br \/>\n<\/p>\n<section class=\"dynamic-content__section dynamic-content__container\">\n<div class=\"dynamic-content__section-container\">\n<div class=\"dynamic-content__figure-container\">\n<figure class=\"dynamic-content__figure\">\n      <img decoding=\"async\" src=\"https:\/\/iris.who.int\/server\/api\/core\/bitstreams\/7493357f-da0e-402d-b406-9a0d939a6486\/content\" alt=\"Guideline on doxycycline post-exposure prophylaxis for sexually transmitted infections among men who have sex with men and transgender women\"><br \/>\n     <\/figure>\n<div class=\"button button-blue-background\"><a target=\"_blank\" href=\"https:\/\/iris.who.int\/server\/api\/core\/bitstreams\/df9e8521-56b9-4f19-8a29-f551821ce975\/content\" onclick=\"sendGaEvent('Download','https:\/\/iris.who.int\/server\/api\/core\/bitstreams\/df9e8521-56b9-4f19-8a29-f551821ce975\/content')\">Download <span>(763.1 kB)<\/span><\/a><\/div><\/div>\n<div class=\"dynamic-content__description-container\">\n<div class=\"row\">\n<div class=\"col-md-8\">\n<div class=\"dynamic-content__description\">\n<h3>Overview <\/h3>\n<p>This guideline provides evidence-informed recommendations on the use of doxycycline post-exposure prophylaxis (PEP) for the prevention of bacterial sexually transmitted infections (STIs) among men who have sex with men and transgender women, populations disproportionately affected by STIs. It presents WHO\u2019s first recommendation on this intervention, developed through systematic review of the available evidence and expert assessment of its benefits, harms, acceptability, feasibility, equity and implementation considerations. The guideline recommends that doxycycline PEP may be offered as part of a comprehensive sexual health package, while emphasizing the importance of monitoring antimicrobial resistance during policy implementation.<\/p>\n<p>The document summarizes the evidence supporting the recommendation, outlines its justification, and provides practical guidance for implementation, including timing of doxycycline use, prioritization of individuals at higher STI risk, integration into sexual health services, equitable service delivery models, and monitoring and evaluation. It also identifies key research gaps, particularly regarding antimicrobial resistance, population-level impact, optimal dosing strategies, integrated service delivery models and implementation research, to inform future policy development and strengthen evidence-based STI prevention.<\/p>\n<div id=\"dynamic-content__accordion\" class=\"dynamic-content__accordion\">\n<h3>Related<\/h3>\n<div class=\"arrowed-link\"><a target=\"_blank\" href=\"https:\/\/www.who.int\/teams\/global-hiv-hepatitis-and-stis-programmes\/stis\/overview\">Technical work on STIs<\/a><\/div>\n<div class=\"arrowed-link\"><a target=\"_blank\" class=\"sf-immutable-selected\" href=\"https:\/\/www.who.int\/health-topics\/sexually-transmitted-infections\">General information on STIs<\/a><\/div><\/div><\/div><\/div>\n<div class=\"col-md-4\">\n<div class=\"dynamic-content__details\">\n<div class=\"detail who-team\">\n<div class=\"label\">WHO Team<\/div>\n<div class=\"value\">\n                 <span><br \/>\nHIV, TB, Hepatitis and STIs (HTH)                 <\/span>\n         <\/div><\/div>\n<div class=\"detail\">\n<div class=\"label\">Editors<\/div>\n<div class=\"value\">World Health Organization<\/div><\/div>\n<div class=\"detail\">\n<div class=\"label\">Number of pages<\/div>\n<div class=\"value\">18<\/div><\/div>\n<div class=\"detail\">\n<div class=\"label\">Reference numbers<\/div>\n<div class=\"value\">\n<div><strong class=\"label-sm\">ISBN: <\/strong><span>978-92-4-012411-0<\/span><\/div><\/div><\/div>\n<div class=\"detail\">\n<div class=\"label\">Copyright<\/div>\n<p>                <a target=\"_blank\" class=\"creativecommons-icons-wrappers\" href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/igo\/deed.en\" rel=\"license\" title=\"Click here to see the details of CC BY-NC-SA 3.0 IGO\"><br \/>\n                        <img decoding=\"async\" src=\"https:\/\/www.who.int\/ResourcePackages\/WHO\/assets\/icons\/cc-icons\/cc.svg\"><br \/>\n                        <img decoding=\"async\" src=\"https:\/\/www.who.int\/ResourcePackages\/WHO\/assets\/icons\/cc-icons\/by.svg\"><br \/>\n                        <img decoding=\"async\" src=\"https:\/\/www.who.int\/ResourcePackages\/WHO\/assets\/icons\/cc-icons\/nc.svg\"><br \/>\n                        <img decoding=\"async\" src=\"https:\/\/www.who.int\/ResourcePackages\/WHO\/assets\/icons\/cc-icons\/sa.svg\"><br \/>\n                <\/a>\n        <\/div><\/div><\/div><\/div><\/div><\/div>\n<\/section>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240124110?rand=6398\" target=\"_blank\">Source link <\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Download (763.1 kB) Overview This guideline provides evidence-informed recommendations on the use of doxycycline post-exposure prophylaxis (PEP) for the prevention of bacterial sexually transmitted infections (STIs) among men who have sex with men and transgender women, populations disproportionately affected by STIs. It presents WHO\u2019s first recommendation on this intervention, developed through systematic review of the available evidence and expert assessment&hellip;<\/p>","protected":false},"author":99035,"featured_media":9528,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":{"give_campaign_id":0,"footnotes":""},"tags":[2953,2950,1458,1828,1281,2951,2952,1391,1826,1205,1827,570],"ground_category":[315,316],"class_list":["post-9527","ground_post","type-ground_post","status-publish","format-standard","has-post-thumbnail","hentry","tag-among","tag-doxycycline","tag-guideline","tag-infections","tag-men","tag-postexposure","tag-prophylaxis","tag-sex","tag-sexually","tag-transgender","tag-transmitted","tag-women","ground_category-2-grounds-tribulation","ground_category-2-1-time-disease"],"fifu_image_url":"https:\/\/iris.who.int\/server\/api\/core\/bitstreams\/7493357f-da0e-402d-b406-9a0d939a6486\/content","_links":{"self":[{"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/ground_post\/9527","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/ground_post"}],"about":[{"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/types\/ground_post"}],"author":[{"embeddable":true,"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/users\/99035"}],"replies":[{"embeddable":true,"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/comments?post=9527"}],"version-history":[{"count":0,"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/ground_post\/9527\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/media\/9528"}],"wp:attachment":[{"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/media?parent=9527"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/tags?post=9527"},{"taxonomy":"ground_category","embeddable":true,"href":"https:\/\/godshand.link\/en_gb\/wp-json\/wp\/v2\/ground_category?post=9527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}